Observe Carefully (one)lumefantrine will decrease the level or impact of exemestane by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. For individuals acquiring exemestane by using a potent CYP3A4 inducer the encouraged dose of exemestane is 50 mg day-to-day following a food.Adjuvant treatment of postmenopausal Gals with e